Materiobiology & Nanobiomaterials
Enzymatic route towards Virus-Polymer hybrid nanoparticles
Engineered bionanostructures have great potential in drug delivery systems, nanoelectronics, liquid crystals and biosensors. Virus particles (VPs) are promising bionanomaterials in the aforementioned applications and have so far been used for drug delivery as nanocarrier platforms, nanoreactors, probes for imaging and sensing platforms.
Applications of VPs depend on the addition of new functionalities via genetic or synthetic modifications adding properties such as responsiveness, capacity of loading cargoes and decrease immunogenicity.
We use amongst others Tobacco Mosaic Virus (TMV) and Potato Virus X (PVX) to investigate alternative modification routes, ways to achieve new viral structural morphologies and use these in biomedical applications such as gene delivery and other therapeutic approaches.
The creation of novel virus morphologies using genetically modified virus particles with biomineralization capabilities.